Patients with hypophosphatasia can be affected by serious renal complications. Inhibition of bone mineralisation with hypophosphatasia can lead to the following secondary conditions:
- Hypercalcaemia
- Hyperphosphatemia
- Hypercalciuria
Ultrasound scan of kidneys illustrating calcium deposits (white arrow) with posterior acoustic shadowing (black arrow).
Barvencik F et al 2011
Barvencik F et al. Osteoporos Int 2011; 22: 2667-2675.
Mohn A et al. Acta Paediatr 2011; 100: 43-46.
Eade AW et al. Ann Rheum Dis 1981; 40: 164-170.
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